Well I have a neca classic masked predator from the predators series and he's still in the box. But recently I moved the shelf and the figure fell over and I noticed the card back separated from the plastic a bit and I am really frustrated by this because I was going to keep it in the box to keep it's value since the figure is already selling high in price on ebay and I can imagine it will increase. Should I open it entirely now or does it still count as unopened?

I'd have to see a picture of it to see if it's damaged enough to be considered "opened"... but really you should just do which ever would make you the most happy. Toy prices and the secondary market are such a fickle thing that it's hardly worth watching. Thousands of "hot" toys from the past 20 years are worth barely retail anymore.